Categoria
Ketoconazol [Inn-Spanish]
Marchi,
Ketoconazol [Inn-Spanish]
Analoghi
Ketoconazol [Inn-Spanish]
Marchi miscela
No information avaliable
Ketoconazol [Inn-Spanish]
Formula chimica
C26H28Cl2N4O4
Ketoconazol [Inn-Spanish]
RX link
http://www.rxlist.com/cgi/generic/ketocon.htm
Ketoconazol [Inn-Spanish]
FDA foglio
Ketoconazol [Inn-Spanish]
DMS (foglio di materiale di sicurezza)
Ketoconazol [Inn-Spanish]
Sintesi di riferimento
Heeres J. et al. US Pat. 4,144,346 (1979)
Ketoconazol [Inn-Spanish]
Peso molecolare
531.43 g/mol
Ketoconazol [Inn-Spanish]
Temperatura di fusione
146 oC
Ketoconazol [Inn-Spanish]
H2O Solubilita
0,0866 mg / L
Ketoconazol [Inn-Spanish]
Stato
Solid
Ketoconazol [Inn-Spanish]
LogP
3.651
Ketoconazol [Inn-Spanish]
Forme di dosaggio
Compresse, shampoo, crema, sospensione
Ketoconazol [Inn-Spanish]
Indicazione
Per il trattamento delle seguenti infezioni fungine sistemiche: candidosi, candidosi mucocutanea cronica, mughetto orale, candiduria, blastomicosi, coccidioidomicosi, istoplasmosi, chromomycosis e paracoccidioidomicosi.
Ketoconazol [Inn-Spanish]
Farmacologia
Ketoconazolo, come il clotrimazolo, fluconazolo, itraconazolo e miconazolo, è un agente antimicotico imidazolico.
Ketoconazol [Inn-Spanish]
Assorbimento
Moderato
Ketoconazol [Inn-Spanish]
Tossicita
Epatotossicità, LD50 = 86 mg / kg (per via orale nel ratto)
Ketoconazol [Inn-Spanish]
Informazioni paziente
Shampoo: May be irritating to mucous membranes of the eyes and contact with this area should be
avoided.
There have been reports that use of the shampoo resulted in removal of the curl from permanently waved hair.
Tablet: Patients should be instructed to report any signs and symptoms which may suggest liver
dysfunction so that appropriate biochemical testing can be done. Such signs and symptoms may include unusual fatigue,
anorexia, nausea and/or vomiting, jaundice, dark urine or pale stools
Ketoconazol [Inn-Spanish]
Atto interessato organismi
Funghi